TERTIARY LYMPHOID ORGANS IN THE INFLAMMATORY MYOPATHY ASSOCIATED WITH PD-1 INHIBITORS

Abstract Background Programmed cell death 1 inhibitors have revolutionized therapy for cancer by their outstanding effectiveness.However, they may cause adverse effects, among which inflammatory myopathy is one of the most disabling.To elucidate its mechanism, we analysed muscle biopsies and compared them with other inflammatory myopathies.Methods

Mitral regurgitation is uncommon with left atrial myxoma.The DIGESTIVE ENZYMES echocardiographic assessment of presence of mitral regurgitation and its severity are impaired by the presence of left atrial myxoma.We describe an uncommon association of left atrial myxoma with coronary artery disease and mitral regurgitation.MR was reported as mild Sh